The i-port® functions as a medication delivery channel directly into the subcutaneous tissue (the tissue layer located just beneath the skin). When applying the i-port®, an insertion needle guides a soft cannula (a small, flexible tube) under the skin. Once applied, the insertion needle is removed and only the soft cannula remains below the skin, acting as the gateway into the subcutaneous tissue.

To inject through the i-port®, the needle of a syringe or insulin pen is used. The needle remains above the surface of the skin, while the medication is immediately delivered through the soft cannula and into the subcutaneous tissue. The i-port® can accommodate 75 injections, and be worn for up to 72 hours.